On February 2, 1846, Francis Adolphus Muir went to the home of his friend Captain William Dandridge Epes. Muir and Epes were two of Dinwiddie County, Virginia's most prominent and respected men. They had business to discuss; Muir held bonds amounting to $3,200 against Epes, the balance owed by Epes for a tract of land he bought from Muir. Muir was invited to stay for dinner when their business was concluded.
According to Mrs. Epes, her husband told Muir about a deer he had seen in the woods and asked Muir to accompany him when he went to kill it. Muir agreed, and the two men left together on horseback. Epes returned alone and told his wife that Muir had found it necessary to go to Brunswick and would not be staying for dinner. Muir was not seen again in life.